Sofadon area is inhabited since prehistoric times. The first known inhabitants are the Pelasgians (pre-Greeks), who the cult of Athena Itonia possibly comes from. The prehistoric Arni was, according to Homer and Pausanias, the cradle of the Aeolians. The biggest event in the Thessalian area, Kuaria, in honor of the god Apollo is likely to have taken place in the riverside area of Mascholouriou community.
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